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We then divided the period of time after the initial diagnosis of anal cancer into the following phases of treatment: (1) initial care, (2) continuation care, and (3) terminal care.

Anal cancer-related costs were estimated using age- and sex-matched controls who were assigned the same index date (i.e., both cases and controls were monitored from the date of cancer detection until their death or the end of Medicare claims).

We first estimated survival time for patients with anal cancer from the date of diagnosis until their death or the end of the follow-up period, which was defined as the end of Medicare claims.

The 15 SEER registries collect detailed information about cancer incidence and survival in defined geographic areas, including clinical, demographic, and cause-of-death data for persons with cancer.

Of the US population, 25% is included in the SEER registries.

The patient identification algorithm is presented in Supplementary Appendix 2.

The major portions of cancer treatment costs are incurred in the initial phase when the disease is diagnosed and in the terminal phase when the physicians extend their efforts to improve the patient’s quality of life.




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Many holders of the title now use Patwari as their family last name in Karnataka and a few other parts of South India. The peer of a patwari in Maharashtra and Karnataka is the talati.